You need to pick an AI vendor. Anthropic says they’re the safest. OpenAI says they’re the most capable. Meta says you can inspect everything yourself with LLaMA. They all sound great in the marketing materials.
Here’s the problem: each vendor takes a fundamentally different approach to AI safety. Constitutional AI, RLHF, open-source community safety—these aren’t just technical distinctions. They affect what compliance requirements you can meet, what happens when something goes wrong, and how much you’ll spend getting it right. This comparison builds on our comprehensive guide to AI safety and interpretability breakthroughs, focusing specifically on how to evaluate and select the right vendor for your enterprise needs.
Get this wrong and you’re looking at compliance failures, security incidents, or spending a fortune on safety features you don’t need.
This article gives you a systematic comparison of safety methodologies, enterprise features, and practical evaluation criteria. By the end, you’ll have a clear framework for matching vendor strengths to your specific business requirements.
How Do Anthropic, OpenAI, and Meta FAIR Approach AI Safety Differently?
The three major vendors have bet on different solutions to the same problem: how do you make AI systems behave reliably?
Anthropic uses Constitutional AI, where the model argues with itself about right and wrong. One part generates potentially problematic content, another critiques it, and a third revises based on explicit principles—including ones derived from the UN Declaration of Human Rights. Because these principles are documented, you get auditable behaviour. You can point to the specific principles that guided a decision.
OpenAI primarily relies on RLHF (Reinforcement Learning from Human Feedback). Human raters evaluate outputs, and the model learns to produce responses matching their preferences. It works well for output quality, but it mainly addresses surface-level alignment without verifying whether internal reasoning is actually safe.
Meta takes the open-source route. You get the model weights, you can inspect everything, and the community does red-teaming and safety research. It’s transparent by design, but you’re on the hook for implementing and maintaining your own safety guardrails.
What matters for your decision:
Constitutional AI aims for consistency through encoded principles. You get predictable behaviour, though it can’t confirm whether ethical constraints are reflected in internal reasoning.
RLHF aligns with human preferences, which sounds good until you realise it inherits biases from those raters. It may also be less predictable across contexts.
Open-source gives you transparency and customisation, but you’re responsible for everything. If you have ML engineers who know what they’re doing, that’s an advantage. If you don’t, it’s a liability.
For regulated sectors, these differences translate into procurement requirements. Anthropic achieved ISO/IEC 42001:2023 certification—the first international standard for AI governance—which provides auditable ethical frameworks that satisfy regulatory scrutiny.
What Are AI Safety Levels and How Do They Affect Enterprise Deployment?
Anthropic developed AI Safety Levels (ASL) as a risk classification system tying capability advancement to demonstrated safety measures.
The system runs from ASL-1 (no meaningful catastrophic risk) through ASL-2 (current frontier models requiring safety protocols) to ASL-3+ (increasing capability for potential misuse).
To make this concrete: ASL-2 might be a customer service chatbot handling general enquiries with human oversight for edge cases. ASL-3 would involve systems making autonomous decisions in high-stakes contexts—medical diagnosis support or financial risk assessment where errors could cause direct harm.
Higher ASL ratings mean more stringent access controls, monitoring, and containment. General productivity applications likely need ASL-2 requirements. Systems making high-stakes decisions affecting people’s lives need higher-tier requirements.
OpenAI has its Preparedness Framework focusing on pre-deployment risk assessment. Both frameworks address similar concerns but structure them differently.
Here’s the practical side: AI risk management needs to sit alongside your broader enterprise risk strategies, right next to cybersecurity and privacy. High-risk systems may require you to halt development until risks are managed. For many SMB use cases, standard safety protocols from any major vendor will do the job. But if you’re in healthcare, finance, or automated decision-making affecting people’s access to services, you need to work out which safety level applies.
Organisations with AI Ethics Review Boards will find Anthropic’s framework easier to audit.
Which AI Provider Offers Better Interpretability and Explainability Features?
Let’s get the terminology straight. Interpretability is about understanding how a model works internally—architecture, features, and how they combine to deliver predictions. Explainability is about communicating model decisions to end users. Both matter for compliance, but different audiences need different levels of detail.
Anthropic leads in interpretability research. They’ve published work identifying 30 million features as a step toward understanding model internals and have moved from tracking features to tracking circuits that show steps in a model’s thinking. This matters if you need to understand why the model behaves the way it does. For deeper technical context on these research breakthroughs, see our article on how AI introspection works and what Anthropic discovered.
OpenAI provides audit logging and usage analytics through ChatGPT Enterprise, including admin dashboards with conversation monitoring. You see what’s happening at the usage level but get less insight into model internals.
Meta’s open-source LLaMA allows direct model inspection and custom explainability implementations. If you have the expertise, you can integrate it with any framework. If you don’t, you’re on your own.
For compliance, explainability supports documentation, traceability, and compliance with GDPR, HIPAA, and the EU AI Act. If your AI denies someone’s insurance claim, you may need to explain the key factors in that denial.
A practical way to think about it:
- Need to satisfy regulators with detailed technical documentation? Anthropic’s interpretability research gives you the most ammunition
- Need audit trails and usage monitoring? OpenAI Enterprise provides solid dashboards
- Need custom explainability for specific use cases and have ML engineers? LLaMA gives you flexibility
How Do Vendor Safety Frameworks Compare for Enterprise Risk Management?
Each vendor has published a framework describing their commitments. Here’s what matters for enterprise risk management.
Anthropic’s Responsible Scaling Policy ties capability advancement to demonstrated safety measures. They’ve deployed automated security reviews for Claude Code and offer administrative dashboards for oversight.
OpenAI’s Preparedness Framework focuses on pre-deployment risk assessment. They’ve added IP allowlisting controls for enterprise security and their Compliance API integrates with third-party governance tools.
Meta’s Frontier AI Framework emphasises transparency and community-driven safety research. With open weights, anyone can inspect and improve safety measures. But “community-driven” means you’re relying on others to find and fix issues.
For vendor evaluation, here’s what it means in practice:
- Anthropic provides the clearest safety commitments and most auditable frameworks
- OpenAI offers structured risk assessment with good enterprise integration
- Meta enables custom risk controls but requires you to implement them
With AI procurement, add data leakage, model bias, and explainability to your diligence checklist. Vendor due diligence includes assessing financial stability, cybersecurity posture via certifications, and references.
Contract negotiation is where risk management gets real. Contracts should define SLAs, data protection requirements, regulatory compliance obligations (GDPR, HIPAA), and incident response plans. For a complete framework on implementing AI governance structures, including ISO 42001 requirements, see our guide to building AI governance frameworks.
What Are the Cost Differences for Enterprise AI Safety Features?
Let’s talk numbers.
OpenAI tends to be most expensive per million tokens. GPT-4 Turbo runs around $10 output per 1M tokens. GPT-4o mini is cheaper at $0.60 input / $2.40 output per 1M tokens.
Anthropic’s Claude is positioned slightly cheaper. Claude Sonnet 4 runs $3 input / $15 output per 1M tokens. Claude Opus is premium at $15 input / $75 output per 1M tokens.
For subscriptions: Claude Pro is $20/month with 5x usage. Claude Max starts at $100+/month for intensive use. ChatGPT Plus is $20/month for GPT-4o. Pro is around $200/month.
LLaMA is free to download. But “free” is doing heavy lifting there.
Hidden costs are where real budgeting happens:
- OpenAI: API overage charges, custom fine-tuning requiring separate pricing, professional services for integrations
- Anthropic: Premium seat upgrades adding 30-50% to base costs, advanced analytics requiring higher tiers
- LLaMA: Infrastructure, ML engineering for safety, ongoing maintenance, incident response
Total cost of ownership captures training, enablement, and infrastructure overhead. For 100 developers, training alone can exceed $10,000+.
For SMBs:
- No ML engineers? Hosted solutions (Anthropic, OpenAI) are more cost-effective despite higher per-token costs
- Have ML engineers and stable workloads? Self-hosted LLaMA may prove more cost-effective over time
- Variable or short-term workloads? Cloud remains advantageous
Open-Source LLaMA vs Closed-Source Claude and GPT: Which Is Safer for Enterprise?
The answer depends on what “safer” means for you and what capabilities you have in-house.
Open-source provides transparency. You inspect model weights and behaviour. You control your data—it never leaves your infrastructure. That addresses privacy concerns that led JPMorgan to restrict ChatGPT for their 250K staff.
Closed-source vendors manage safety updates and handle emerging threats. They have dedicated teams finding and fixing vulnerabilities.
Here’s the trade-off:
LLaMA (open-source)
- Full transparency and inspection
- Data stays on your infrastructure—important for GDPR and HIPAA
- You implement and maintain guardrails
- You handle incident response
- Requires ML engineering capability
Claude and GPT (closed-source)
- Managed safety updates
- Data handled per enterprise agreements with varying guarantees
- Safety depends on vendor’s ongoing commitment
Claude emphasises safety with a context window up to 500,000 tokens. ChatGPT offers up to 128,000 tokens with image generation and custom GPTs.
Many enterprises find that a combination works best—closed-source for high-stakes applications, open-source for lower-risk tasks or when data must stay on-premises.
How to Evaluate AI Vendors for Safety and Interpretability
Here’s a practical evaluation framework.
Start with use case risk assessment
High-stakes decisions need stronger safety guarantees. Define what “high stakes” means for you. Is the AI making recommendations a human reviews, or autonomous decisions affecting people directly?
Evaluate the vendor’s track record
Look for published safety research, third-party audits, transparent incident reporting, and specific technical documentation. Be wary of vague claims or vendors unwilling to discuss specific safety measures.
Request specific compliance documentation
SOC 2 Type II for general security, HIPAA BAA for healthcare data, GDPR DPA for EU data subjects, ISO 27001 for information security. Requirements depend on your industry and data types.
Test interpretability during trials
Don’t take their word for it. Run realistic scenarios and see if you get the explanations and audit trails you need. Our AI safety evaluation checklist provides specific testing criteria and security considerations for your vendor evaluation process.
Ask hard questions
Where is data processed and stored? What are retention policies? Who can access your data? Is data used for training? What’s the breach notification process?
Vague responses indicate immature privacy practices.
Identify red flags
Watch for inability to provide specific safety documentation, reluctance to discuss incidents, no published safety research, vague interpretability claims, missing certifications, and aggressive timelines skipping security review.
Match vendor strengths to your needs
High customisation needs favour OpenAI’s ecosystem depth. Modular AI agent workflows align with Anthropic’s MCP architecture. Regulated industries justify Anthropic’s premium for compliance-first architecture. If data minimisation is existential, choose Anthropic.
Keep in mind that 70% of organisations don’t trust their decision-making data. Before worrying about vendor selection, make sure your data house is in order.
FAQ Section
What certifications should I require from my AI vendor?
SOC 2 Type II for general security, HIPAA BAA for healthcare data, GDPR DPA for EU data subjects, ISO 27001 for information security. Requirements depend on your industry and data types.
Can I use multiple AI vendors for different safety requirements?
Yes. Many enterprises use closed-source for high-stakes applications and open-source for lower-risk tasks or when data must stay on-premises. This requires consistent governance across platforms.
How do I know if an AI vendor’s safety claims are legitimate?
Look for published safety research, third-party audits, transparent incident reporting, and specific technical documentation. Beware vague claims or unwillingness to discuss specifics.
What is the difference between interpretability and explainability?
Interpretability refers to understanding how a model works internally, while explainability focuses on communicating decisions to end users. Both matter for compliance, but different audiences need different detail levels.
How often do AI vendors update their safety measures?
Frequency varies. Anthropic publishes regular research updates, OpenAI releases Preparedness Framework updates quarterly, Meta relies on community contributions. Request the vendor’s update cadence during evaluation.
Is Constitutional AI safer than RLHF for enterprise use?
Neither is objectively “safer.” Constitutional AI produces consistent, principle-based behaviour. RLHF aligns with human preferences but may be less predictable. Choose based on whether you prioritise consistency or human-like responses.
What questions should I ask AI vendors about data privacy?
Ask where data is processed and stored, retention policies, who can access your data, whether data trains their models, contractual guarantees, and breach notification processes. Vague responses indicate immature practices.
Which vendor makes guardrail configuration easiest?
Anthropic provides pre-configured guardrails with clear documentation. OpenAI offers more customisation but requires more setup. LLaMA gives complete control but requires building guardrails from scratch. Choose based on internal AI expertise.
What are the red flags when evaluating AI vendors for safety?
Inability to provide safety documentation, reluctance to discuss incidents, no published safety research, vague interpretability claims, missing certifications, and aggressive timelines skipping security review.
Should SMBs prioritise safety features over capability when choosing AI vendors?
For most SMB use cases, baseline safety from major vendors is adequate. Regulated industries need strong compliance features; general productivity applications can focus on capability with standard safety controls.
How do AI providers handle security incidents differently?
Anthropic and OpenAI manage incidents internally with customer notification per agreements. With LLaMA, you handle incidents yourself. Evaluate incident history and response time commitments when comparing.
What is the minimum internal expertise needed for each AI deployment option?
Hosted solutions need minimal AI expertise—focus on governance and use case management. Self-hosted LLaMA requires ML engineering for deployment, safety implementation, and ongoing maintenance.